Antibacterial and anti-inflammatory activities of chitosan/ copper complex coating on medical catheters: In vitro and in vivo

The article is about a new coating for medical catheters that has antibacterial and anti-inflammatory activities. The coating is made of chitosan with copper ions grafted in it using a pneumatic spraying method. The authors tested the properties and performance of the coating in vitro with Escherichia coli and Staphylococcus aureus suspensions, and in vivo with mice implanted with catheters. The authors found that the coating reduced bacterial adhesion and biofilm formation, as well as inflammation and tissue damage. The authors concluded that the coating could improve the safety and efficacy of medical catheters.

Antibacterial and anti-inflammatory activities of chitosan/copper complex coating on medical catheters: In vitro and in vivo – PubMed (nih.gov)

https://doi.org/10.1002/jbm.b.35047

Antibacterial and anti‐inflammatory activities of chitosan/copper complex coating on medical catheters: In vitro and in vivo – Gu – 2022 – Journal of Biomedical Materials Research Part B: Applied Biomaterials – Wiley Online Library